According to the Annals of Epidemiology side effects associated with androgen deprivation therapy (ADT) has been linked to cataract. ADT was defined as at least one dose of gonadotropin releasing hormone agonist or orchiectomy within 6 months after prostate cancer diagnosis.
Karmanos Cancer Institute in Detroit examined the risk of cataract association with ADT among 65,852 prostate cancer patients. Researchers found that the use of gonadotropin releasing hormone agonist was associated with modest increase in cataract incidence. Orchiectomy was also associated with an increase in risk of cataract among men with no history of cataract prior to prostate cancer diagnosis. Further study is needed to provide additional information to support or refute these finding, according to authors.
Advanced Ocular Care News, January/March 2011 pg. 9
Cynthia Matossian, MD