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What Ever Happened to Dilation Reversal Drops?

Posted on: Thursday, September 29, 2011
Author: Matossian Eye Associates

Tags: eye exam, dialation, dapiprazole, pupil constriction

Pupillary dilation is a crutial part of your eye exam, and a most valuable step toward protecting your eye health.  But it is also greatly disliked by most patients.  Dilation drops typically take 4-6 hours to wear off, and during that time blurred vision and light sensitivity remain.  Released in 1991, Rev-Eyes (dapiprazole), promised to revolutionize the practice of eye care by providing a means to reverse dilation.  The new drop counteracted dilation by stimulating pupil constriction.  The reality of the situation was that the drop tended to work slow, often taking a few hours to return pupils to their normal state.  The drop also caused unpleasant side effects such as stinging upon instillation and red eyes in the majority of patients.  It was also expensive, costing 4-5x more than the dilation drops.  Rev-Eyes are no longer available in the United States, but hope remains for an alternative.   
Rebecca Mueller, O.D.



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